EB. 133: The Sugar Diet/Honey Diet and FGF21: The Research

EB. 133: The Sugar Diet/Honey Diet and FGF21: The Research

The Energy Balance Podcast · 2025-05-20
01:32:31
In this episode we discuss: What are the sugar diet and other related diets like the honey diet, fairy princess diet, and fruit till noon dietsWhether FGF21 is responsible for the weight loss seen on these dietsThe effects of the sugar diet on muscle massWhether FGF21 really extends lifespanHow to increase FGF21 levels and whether it’s really good for your health

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Click here to check out the show notes: https://www.jayfeldmanwellness.com/eb-133-the-sugar-diet-honey-diet-and-fgf21-the-research/

Timestamps:

0:00 – intro

1:00 – the sugar diet, honey diet, fairy princess diet, and fruit-till-noon diets as discussed by Cole Robinson, Mark Bell, Anabology, Noah Ryan, celestialbe1ng, and others

6:35 – my experience on a high-sugar diet and what the sugar diet means for the health world

11:17 – what is FGF21?

15:54 – how low-protein diets trigger the release of FGF21

20:00 – the context of FGF21 on low-protein diets and the reasons for its effects: is this really beneficial?

26:15 – the long-term effects of FGF21 on body fat, muscle mass, and metabolic health

33:16 – how the sugar diet compares to low-carb diets

35:55 – high-carb low-protein diets vs. high-fat low-protein diets on FGF21

37:34 – low-protein diets increase your metabolism due to stress: brown fat, uncoupling, and energy expenditure

43:59 – FGF21’s role in stress, energy conservation, and hibernation

49:56 – FGF21 and cortisol: is FGF21 a stress hormone?

54:09 – FGF21 and hormesis: is FGF21 hormetic?

56:10 – FGF21 and liver fat production go hand-in-hand

59:11 – carb-induced increase in FGF21 is activated by reductive stress

1:05:04 – the role of FGF21 in de novo lipogenesis as an adaptive response to stress

1:10:47 – carb-induced FGF21 causes fat gain and sympathetic activity

1:14:29 – does FGF21 cause metabolic syndrome, diabetes, NAFLD, cardiovascular disease, and obesity?

1:21:08 – does FGF21 extend lifespan? if so, is it worth it?

1:27:03 – can you lose weight and extend lifespan without a protein-deficient diet?

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