Conan O'Brien

Conan O'Brien

MeSsy with Christina Applegate & Jamie Lynn Sigler · 2025-05-13

This week, Christina and Jamie are joined by Conan O'Brien. They discuss perspective, the importance of having morals, the circle of life, and much more.



Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

Audio Engineer: Josh Windisch

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This episode is sponsored by:

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MeSsy with Christina Applegate & Jamie Lynn Sigler

On this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

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